Loyola University New Orleans is a private institution that was founded in 1912. It has a total undergraduate enrollment of 3,200, its setting is suburban, and the campus size is 26 acres. It utilizes a semester-based academic calendar. Loyola University New Orleans's ranking in the 2014 edition of Best Colleges is Regional Universities (South), 9. Its tuition and fees are $36,610 (2013-14).

Loyola is located in the historic Audubon Park District on St. Charles Avenue. Its original campus, now called the Main Campus, was founded on a tract of land purchased by the New Orleans Jesuits in 1889. The purchased portion of land was much larger than the current day campus; in fact, the original land purchase contained the land now occupied by both Loyola and Tulane universities and Audubon Place. Through the next twenty years, portions of the original land purchase were sold to different entities to raise money for the new university, resulting in the current Main Campus area of 19 acres.

By the 1950s, most of the original campus had been developed and the university looked around for areas where it could expand. In the 1960s, J. Edgar Monroe, a major benefactor of the university, donated to Loyola a large undeveloped tract of land in Metairie where the university could either expand or move its entire location. After reviewing its options, including the sale of the original campus to Tulane University, the university decided to remain on St. Charles Avenue, subsequently selling off its property in Metairie in ten years as a condition of the donation.

The Louis J. Roussel, Jr., Performance Hall on the Loyola campus, which stages symphony concerts, is named for the late New Orleans businessman Louis J. Roussel, Jr.

The closure of St. Mary's Dominican College in 1984 provided an opportunity for Loyola to expand its campus. After renovation of the closed college and some new construction, the Broadway Campus was opened in 1986, with several university offices and programs, the school of law most significantly, moving to the new campus.